Valle Palomo (CIB, CSIC)
Date & location: Thu 24 Jan 2019 12:00:00 GMT+0200 (CEST), Conference Room, Serrano 121 (CFMAC)
Neurodegenerative diseases are complex pathologies with unknown etiology that lead to neural death. Their unknown etiology and complex molecular mechanisms has prevented the finding of effective therapies in the clinic. Biosensors allow for a detailed study of biological processes. Specifically, Quantum Dots are nanoparticles formed by CdSe core and a ZnS coating that offer unique photo luminescent properties. They present an improved photostability, broad absorption and narrow emission spectra that enables improved detection sensitivity and multiplexed analysis. In our group we use QDs as immunostaining platform in human models of disease and also as biosensors of key enzymatic processes. Parallely, we use chemical biology as a tool to understand diseases and find effective treatments.